Metabolism of Amino Acids and Nucleotides – BBCCT-113 Assignment Answers

Metabolism of Amino Acids and Nucleotides

Core Course in Biochemistry
Course Code: BBCCT-113
Assignment Code: BBCCT-113/TMA/2025
Maximum Marks: 100

Note: Attempt all questions. The marks for each question are indicated against it. Write all answers in your own words; do not copy from the course material.

PART-(A) (50 Marks)

1. a) Draw nitrogen cycle and explain biological nitrogen fixation (5)
   b) Write short note on Marasmus (5)
2. Give an overview of urea cycle (10)
3. Explain the catabolism of amino acids that are converted to pyruvate (10)
4. a) Explain the following disorders of amino acid metabolism: Homocystinuria (5)
   b) Hartnup disease (5)
5. a) Describe biosynthesis of non essential amino acids of aromatic amino acid family (5)
   b) What are catecholamines? (5)

PART-(B) (50 Marks)

6. Explain de novo synthesis of UMP. Describe the steps (10)
7. a) How purine synthesis is regulated? (6)
   b) Explain the structure of type I RNR (4)
8. a) Enlist any two inhibitors of nucleotide synthesis with their mechanism of action, enzyme inhibited and their use in medicine (5)
   b) Elaborate on the fate of uric acid in the degradation of purine nucleotides (5)
9. Compare catabolism of purine and pyrimidine nucleotides (10)
10. a) Describe briefly the signs and symptoms of SCID (5)
    b) Distinguish between white and brown adipose tissue (5) 

Each answer is crafted with extended detail in simple language to meet and exceed IGNOU’s expectations.