Explain the fundamental principles of cell theory. Compare and contrast the structural and functional differences between prokaryotic and eukaryotic cells.

Fundamental Principles of Cell Theory and Comparison of Prokaryotic and Eukaryotic Cells

Fundamental Principles of Cell Theory

Cell theory is a cornerstone of modern biology that explains the basic structure and function of all living organisms. It was developed in the 19th century by scientists like Matthias Schleiden, Theodor Schwann, and Rudolf Virchow. The main principles of cell theory are:

  1. All living organisms are made up of one or more cells.
    Whether unicellular (like bacteria) or multicellular (like humans), every organism is composed of cells.
  2. The cell is the basic structural and functional unit of life.
    All physiological functions of organisms occur within cells or are mediated by cells.
  3. All cells arise from pre-existing cells.
    This idea, proposed by Rudolf Virchow, means new cells are produced by the division of existing ones, not from non-living material.

Modern additions to the theory include the concepts that:

  • Cells contain hereditary information (DNA) that is passed on during cell division.
  • All energy flow (metabolism and biochemistry) occurs within cells.

Comparison of Prokaryotic and Eukaryotic Cells

Cells are broadly categorized into two types: prokaryotic and eukaryotic. These differ significantly in structure and function.

Feature Prokaryotic Cells Eukaryotic Cells
Size Generally smaller (0.1 – 5 µm) Larger (10 – 100 µm)
Nucleus No true nucleus; DNA is in nucleoid region Has a well-defined nucleus enclosed by a nuclear membrane
Membrane-bound Organelles Absent Present (e.g., mitochondria, ER, Golgi apparatus)
DNA Single, circular DNA Linear DNA within the nucleus, associated with histones
Cell Division Binary fission Mitosis and meiosis
Examples Bacteria and Archaea Plants, animals, fungi, protists
Ribosomes Smaller (70S) Larger (80S)
Cell Wall Usually present (made of peptidoglycan in bacteria) Present in plants (cellulose) and fungi (chitin), absent in animals

Conclusion

Cell theory provides a universal explanation for the existence and functions of all living organisms. While prokaryotic and eukaryotic cells differ in complexity, both serve as the fundamental building blocks of life. Understanding their differences helps in studying cell biology, genetics, and the evolution of life forms.

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