Name the nutrients involved in the following diseases: Pernicious anemia, Scurvy, Xerophthalmia, Pellagra, Rickets.

Introduction

Nutrition plays a pivotal role in maintaining human health. Deficiencies in specific nutrients often lead to distinct diseases. Understanding which nutrients are involved in particular disorders helps in both diagnosis and prevention. In this post, we explore five well-known deficiency-related diseases and the key nutrients whose lack causes them.

1. Pernicious Anemia

Involved Nutrient: Vitamin B12 (Cobalamin)

Pernicious anemia is caused by a deficiency of vitamin B12, which is essential for red blood cell production and neurological function. This condition often results from the inability of the stomach to produce intrinsic factor, a protein necessary for B12 absorption.

  • Symptoms: Fatigue, weakness, memory loss, and neurological complications
  • Sources of Vitamin B12: Animal products like meat, eggs, milk, and fortified cereals

2. Scurvy

Involved Nutrient: Vitamin C (Ascorbic Acid)

Scurvy is caused by a prolonged deficiency of vitamin C, which is crucial for collagen synthesis, wound healing, and immune function. Vitamin C also acts as an antioxidant.

  • Symptoms: Bleeding gums, joint pain, weakness, anemia, and delayed wound healing
  • Sources of Vitamin C: Citrus fruits, berries, tomatoes, broccoli, and bell peppers

3. Xerophthalmia

Involved Nutrient: Vitamin A

Xerophthalmia is a progressive eye disorder caused by vitamin A deficiency. It can lead to dryness of the conjunctiva and cornea, night blindness, and ultimately complete blindness if untreated.

  • Symptoms: Night blindness, dry eyes, corneal ulcers, and vision loss
  • Sources of Vitamin A: Liver, dairy products, eggs, and orange-colored fruits and vegetables like carrots and mangoes

4. Pellagra

Involved Nutrient: Niacin (Vitamin B3)

Pellagra results from a deficiency of niacin or tryptophan (a precursor of niacin). It is most commonly seen in populations with maize as a dietary staple without proper supplementation.

  • Symptoms: The 3 D’s – Dermatitis, Diarrhea, and Dementia. If untreated, it can lead to death.
  • Sources of Niacin: Meat, fish, nuts, whole grains, and legumes

5. Rickets

Involved Nutrient: Vitamin D

Rickets is a childhood disorder caused by a deficiency of vitamin D, calcium, or phosphate, leading to softening and weakening of bones.

  • Symptoms: Bowed legs, delayed growth, bone pain, and dental issues
  • Sources of Vitamin D: Sunlight exposure, fatty fish, fortified dairy products, and egg yolks

Conclusion

Each of these diseases is directly linked to a specific nutrient deficiency. Ensuring a balanced and nutrient-rich diet is the most effective way to prevent such conditions. Nutritional awareness and early intervention can significantly reduce the prevalence of these deficiency disorders, especially in vulnerable populations.

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