Metabolism

How do nutrients influence the bioavailability and distribution of drugs? Illustrate with suitable examples.

Introduction The interaction between nutrients and drugs is a significant topic in nutritional biochemistry and pharmacology. Nutrients can affect how drugs are absorbed, distributed, metabolized, and eliminated from the body. This is known as a nutrient-drug interaction. Such interactions can influence the bioavailability (the amount of drug that reaches the bloodstream) and the distribution (how […]

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Discuss the role of liver as metabolic organ.

Discuss the Role of Liver as Metabolic Organ The liver is one of the most vital organs in the human body and acts as a central hub for metabolic processes. It regulates the metabolism of carbohydrates, fats, and proteins, and performs detoxification, hormone metabolism, and bile production. 1. Carbohydrate Metabolism Glycogenesis: Conversion of glucose into

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Explain the terms in 2–3 sentences: (a) Substrate level phosphorylation (b) Glycolysis (c) Anaplerotic reactions (d) Chemotrophs (e) Catabolism

Key Metabolic Terms Explained (a) Substrate Level Phosphorylation This is a metabolic process where a phosphate group is directly transferred from a phosphorylated intermediate to ADP, forming ATP. It occurs in glycolysis and the Krebs cycle, independent of the electron transport chain. (b) Glycolysis Glycolysis is the ten-step pathway by which glucose is broken down

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